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By Category: Agents & Toxins

Fine-tuning salmonella-based vaccines

(Medical News Today) An innovative vaccine technology makes use of reengineered salmonella to deliver protective immunity. If such recombinant attenuated salmonella vaccines or RASVs can be perfected, they hold the promise of safe, lost-cost, orally administered defenses against viral, bacterial, fungal and parasitic infections.In a new study, lead author Karen Brenneman and her colleagues at  Read More »

DTRA Contracts for Botulinum Neurotoxin Countermeasures Research

(Global Biodefense) The Defense Threat Reduction Agency (DTRA) this week announced intentions to award three contracts in support of “Medical Countermeasures for Botulinum Neurotoxin Intoxication Focused on Therapeutics and Neuroregenerative Medicines”. DTRA has established a multicenter program in which directed research projects are submitted, evaluated and selected to sponsor a network of collaboration amongst researchers.  Read More »

WSU scientists use ancient teeth, fleas in ‘Black Death’ study

(KREM) A study’s recent finding about a plague that struck 1,500 years ago might seem arbitrary – except that it involves a resurrected pathogen whose secrets, pulled from ancient teeth, can help us understand our world’s emerging diseases. The pathogen, the oldest to be genetically decoded, caused one of the world’s deadliest scourges. By reconstructing  Read More »

Chemist gets US patent for solution to resistance problem

(University of Copenhagen) A chemist based at the University of Copenhagen has just taken out a patent for a drug that can make previously multidrug-resistant bacteria responsive to antibiotics once again. Jørn Bolstad and his chemist colleagues hope that the substance will soon be able to tackle the tremendous problems associated with multidrug resistant tuberculosis  Read More »

MRSA Superbug Protein Structure Solved

(Global Biodefense) A research team from Vanderbilt University Medical Center is the first to decipher the 3-D structure of a protein that confers antibiotic resistance from one of the most worrisome disease agents: methicillin-resistant Staphylococcus aureus (MRSA). The Vanderbilt team’s findings may be an important step in combating the MRSA public health threat over the  Read More »

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